In Vitro Fertilization (IVF) is one of the most frequent methods of conceiving a child. That’s for a good cause. Many of you are familiar with the fundamental concept of in vitro fertilization (IVF), which involves fusing together the male and female reproductive cells outside of the body in culture. But there’s a lot more to IVF than just becoming pregnant. The IVF procedure depends on several factors :
Indications of IVF:
- Is it too late to start a family at 40?
- Diminished Ovarian Function & Age-Related Infertility
- Menstruating women who also have endometriosis
- Obstruction of the sperm passageway, which may lead to male infertility.
The majority of IVF cycles begin around the time of a woman’s menstruation.
Stimulation of the Ovaries and Egg Recovery
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A starting point: the first day
In an IVF cycle, you maximize your chances of success by producing as many mature eggs as possible. The stimulation phase involves the injection of drugs for 8–14 days to induce the ovaries to produce multiple eggs. The medications stimulate (and derivate) two major hormones, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
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Suppression of the Ovaries: 2–4 Weeks
We inhibit the ovaries first with oral contraceptives or a drug called Lupron, and only then do we begin stimulation. Depending on the individual, ovarian suppression might last anywhere from one to four weeks. An ultrasonography and blood test will be done at the conclusion of this period to verify that down-regulation has indeed been accomplished.
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Stimulation of the Ovaries: 8-12 Day Period
On a certain day, the cycle coordinator administers injectable fertility medicines to begin ovulation stimulation Because we may need to adjust a patient’s medicine dosage throughout the day, it’s best if they have their infusions in the evening.
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Monitoring the Cycle Begins on Day 5
After the fifth day of stimulation, regular office visits may begin and will continue every one to 2 days until the aspiration of the follicles.
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Between the eighth and twelfth days of the cycle
Injecting HCG, lupron, or both are used to induce ovulation in women. After injectable fertility medicines have been delivered, the follicles are determined to be developed and the trigger is injected. The fetal aspiration takes place 36 hours well after HCG treatment, therefore timing is critical.
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After HCG Injection, 36-Hour Window for Egg Recovery
You will be able to return home in around two hours. For example, if your goal is to be at the workplace at 9:00 a.m., you should anticipate leaving around 12:00 p.m. Aspiration is a quick and painless process that takes just a few minutes to complete.
Fertilization and ICSI
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Day of Egg Retrieval: Sperm Collection
Sperm count, motility, and morphology all play important roles in male fertility and are important for sperm to successfully meet and enter an egg during natural conception. Preferably, two to seven days before the first sperm specimen, one should refrain from sexual activity. After the seventh day of using fertility medicine, most women will abstain from all sexual activity.
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Day of Egg Retrieval: Fertilization
The sperm and eggs are then brought together for fertilization. Natural fertilization happens in most situations when sperm solution is given to eggs. If necessary, an ICSI injection into the sperm will be performed.
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Hatching assistance
It helps in making the embryo shell thin resulting in higher implantation rates. For patients who are undergoing prenatal genetic testing, this is a common practice.
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5-6 Days After Retrieval: Preimplantation Genetic Test
Prior to the blastocyst stage (usually 5-6 days after conception), early embryonic genetic screening (testing for genomic status, genetic abnormalities, and/or gender assessment) is performed.
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Luteal Phase Support for Embryo Transfer
Between 3 and 5 Days after Egg Retrieval: Embryo Transfer
Fresh blastocyst transfers are often performed during the first three to five days after oocyte retrieval. This week, frozen embryos will be transferred. Anesthesia is not required for this surgery. In certain cases, Valium is used to assist patients to relax their muscles. As a result, each patient must have a designated driver to take them home. Arrive 30 minutes before the embryo transfer, and stay in bed for 30 minutes thereafter.
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Cryopreservation of too many embryos
Cryopreservation (the freezing of embryos) is an option if there are more viable embryos that can be returned to the patient’s uterus.
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Day of Transfer: Luteal Phase Support
A typical technique for directing progesterone is by mixture and vaginal suppositories. At the point when a different blood pregnancy test returns negative, patients are told to keep utilizing the progesterone cream for the rest of the primary long stretches of pregnancy.
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Taking Pregnancy Tests on Days 12 and 14 of Pregnancy
In most cases, the embryos transfer are being by doing a minimum of two prenatal tests. As soon as results are available, your doctor will get in touch with you.
Six cycles are the magic number for IVF success
156,947 women in the UK had 257,398 IVF procedures between 2003 and 2010, according to a new report from the United Kingdom. The mean live fertility rate for couples who had six IVF rounds was 65.3 percent, based on a thorough review that included findings from both fresh and processed embryo transfers.
Until far, most private clinics have assumed that spouses who have undergone three or four failed IVF rounds are less positioned to gain from subsequent cycles. Some fertility clinics may now prescribe more than one round of therapy based on this new information. Visit the Fertility Center in Patna for the best advice.
According to the findings of this research, there are a number of additional relevant stats:
- Those under 35 years of age are the most prone to get the benefits of a six-cycle plan.
- At the six-cycle period, women aged 40-42 who used their own eggs had a live birth rate of 31.5 percent.
- At the six-cycle milestone, women over the age of 42 who used their own eggs had a 4% live birth rate.
- When women 35 and older used donor eggs, they had the same likelihood of success as women under 35, regardless of maternal age.
What Does This Mean For You and Your Fertility Treatments?
A visit with your fertility doctor may be in order if you’re intending on doing IVF or have previously gone through two or more failed rounds of IVF.
Bring up a new topic of discourse: If you have any new information to share with your fertility doctor, do so first. Depending on the age of the mother and the diagnosis of her infertility, some hospitals are more rigid about the maximum number of cycles they prescribe their patients. Future IVF rounds may need moving to a different fertility clinic.
Ask about fertility cycle discounts for several cycles.
Multi-Cycle IVF Discount Program: DVMFC offers two discount program options: a two retrieval and a three retrieval program. Clinics may increase these discounts as a result of these results. Each of these plans has a different structure, so you’ll want to choose something that best fits your circumstances, including your age, the number of eggs harvested, the number of embryos fertilized, and so on.
Consider prenatal genetic testing (PGD/PGS): IVF couples may now use PGD, a newer method, to ensure the viability of embryos. Genetic defects in the embryo are the most common cause of miscarriage. This is nature’s method of avoiding the birth of children with major genetic diseases, many of which have a negative impact on people’s lives or pose a danger to their survival.’ Prior to implantation, patients undergo PGD testing to ensure that their chromosomes are healthy.
In the event that the preponderance of your conceptions is defective, these tests may help you decide whether to utilize donor eggs or not, even if they are more expensive.
Consider using the eggs of a donor: You may have heard that ladies who use donor eggs don’t have to worry about their mother’s age (assuming the woman is physically able to carry the baby). Women over the age of 40, whose IVF success chances are notoriously poor, should pay particular attention to this.
Conclusion:
Couples planning their first Ivf treatment or those who have suffered the heartache of unsuccessful treatments in the past may find fresh hope in this new knowledge. Learn whether you’re eligible for numerous IVF cycles and take advantage of many IVF cycle savings by contacting Best Infertility Center in Bihar now. Our IVF specialists have years of experience in handling complex infertility cases.
